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1

Synthesis of a Sialic Acid α(2−3) Galactose Building Block and Its Use in a Linear Synthesis of Sialyl Lewis X

Hanashima, Shinya, Castagner, Bastien, Esposito, Davide, Nokami, Toshiki, Seeberger, Peter H.

Journal:

Organic Letters

Year:

2007

Language:

english

File:

PDF, 90 KB

english, 2007

2

Structure of Bimolecular Complex between Amphotericin B and Ergosterol in Membrane is Stabilized by Face-to-Face Van der Waals Interaction with their Rigid Cyclic Cores

Nakagawa, Yasuo, Umegawa, Yuichi, Matsushita, Naohiro, Yamamoto, Tomoya, Tsuchikawa, Hiroshi, Hanashima, Shinya, Oishi, Tohru, Matsumori, Nobuaki, Murata, Michio

Journal:

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

3

The core fucose on an IgG antibody is an endogenous ligand of Dectin-1

Manabe, Yoshiyuki, Marchetti, Roberta, Takakura, Yohei, Nagasaki, Masahiro, Nihei, Wataru, Takebe, Tomoyuki, Tanaka, Katsunori, Kabayama, Kazuya, Chiodo, Fabrizio, Hanashima, Shinya, Kamada, Yoshihiro

Journal:

Angewandte Chemie International Edition

Year:

2019

Language:

english

File:

PDF, 1.77 MB

english, 2019

4

Enantiomers of phospholipids and cholesterol: A key to decipher lipid‐lipid interplay in membrane

Hanashima, Shinya, Yano, Yo, Murata, Michio

Journal:

Year:

2020

Language:

english

File:

PDF, 2.53 MB

english, 2020

5

Efficient preparation of human and mouse CD1d proteins using silkworm baculovirus expression system

Kusaka, Hiroki, Kita, Shunsuke, Tadokoro, Takashi, Yoshida, Kouki, Kasai, Yoshiyuki, Niiyama, Harumi, Fujimoto, Yukari, Hanashima, Shinya, Murata, Michio, Sugiyama, Shigeru, Ose, Toyoyuki, Kuroki, Kim

Journal:

Protein Expression and Purification

Year:

2020

Language:

english

File:

PDF, 4.79 MB

english, 2020

6

Synthesis of a Bisubstrate-Type Inhibitor of N-Acetylglucosaminyltransferases

Shinya Hanashima, Shino Manabe, Kei-ichiro Inamori, Naoyuki Taniguchi, Yukishige Ito

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

7

Divergent Synthesis of Sialylated Glycan Chains: Combined Use of Polymer Support, Resin Capture–Release, and Chemoenzymatic Strategies

Shinya Hanashima, Shino Manabe, Yukishige Ito

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 532 KB

english, 2005

8

Synthesis of a Bisubstrate-Type Inhibitor of N-Acetylglucosaminyltransferases

Shinya Hanashima, Shino Manabe, Kei-ichiro Inamori, Naoyuki Taniguchi, Yukishige Ito

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

9

Divergent Synthesis of Sialylated Glycan Chains: Combined Use of Polymer Support, Resin Capture–Release, and Chemoenzymatic Strategies

Shinya Hanashima, Shino Manabe, Yukishige Ito

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 533 KB

english, 2005

10

Systematic Synthesis of Bisubstrate-Type Inhibitors of N-Acetylglucosaminyltransferases

Shinya Hanashima, Kei-ichiro Inamori, Shino Manabe, Naoyuki Taniguchi, Yukishige Ito

Journal:

Chemistry - A European Journal

Year:

2006

Language:

english

File:

PDF, 591 KB

english, 2006

11

Total Synthesis of Dehydroaltenusin.

Shinji Kamisuki, Shunya Takahashi, Yoshiyuki Mizushina, Shinya Hanashima, Kouji Kuramochi, Susumu Kobayashi, Kengo Sakaguchi, Tadashi Nakata, Fumio Sugawara

Journal:

Year:

2004

File:

PDF, 8 KB

2004

12

ChemInform Abstract: Recent Strategies for Stereoselective Sialylation and Their Application to the Synthesis of Oligosialosides

Shinya Hanashima

Journal:

Year:

2012

File:

PDF, 18 KB

2012

13

Silylene/Oxazolidinone Double-Locked Sialic Acid Building Blocks for Efficient Sialylation Reactions in Dichloromethane

Shinya Hanashima, Ken-ichi Sato, Yukishige Ito, Yoshiki Yamaguchi

Journal:

European Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 570 KB

english, 2009

14

Synthesis of the starfish ganglioside LLG-3 tetrasaccharide

Shinya Hanashima, Daichi Ishikawa, Shoji Akai, Ken-ichi Sato

Journal:

Carbohydrate Research

Year:

2009

Language:

english

File:

PDF, 411 KB

english, 2009

15

Sialylation using N-glycolylneuraminyl phosphite donors to synthesize Neu5Gc-containing glycans

Shinya Hanashima, Taku Tomiya, Daichi Ishikawa, Shoji Akai, Ken-ichi Sato

Journal:

Carbohydrate Research

Year:

2009

Language:

english

File:

PDF, 415 KB

english, 2009

16

Total synthesis of dehydroaltenusin

Shinji Kamisuki, Shunya Takahashi, Yoshiyuki Mizushina, Shinya Hanashima, Kouji Kuramochi, Susumu Kobayashi, Kengo Sakaguchi, Tadashi Nakata, Fumio Sugawara

Journal:

Year:

2004

Language:

english

File:

PDF, 233 KB

english, 2004

17

Structural determination of sulfoquinovosyldiacylglycerol by chiral syntheses

Shinya Hanashima, Yoshiyuki Mizushina, Takayuki Yamazaki, Keisuke Ohta, Shunya Takahashi, Hiroyuki Koshino, Hiroeki Sahara, Kengo Sakaguchi, Fumio Sugawara

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

18

Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases α and β

Madoka Watanabe, Shinya Hanashima, Yoshiyuki Mizushina, Hiromi Yoshida, Masahiko Oshige, Kengo Sakaguchi, Fumio Sugawara

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

19

Synthesis of sulfoquinovosylacylglycerols, inhibitors of Eukaryotic DNA Polymerase α and β

Shinya Hanashima, Yoshiyuki Mizushina, Takayuki Yamazaki, Keisuke Ohta, Syunya Takahashi, Hiroeki Sahara, Kengo Sakaguchi, Fumio Sugawara

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 264 KB

english, 2001

20

Synthesis and binding analysis of unique AG2 pentasaccharide to human Siglec-2 using NMR techniques

Shinya Hanashima, Ken-ichi Sato, Yuko Naito, Hiromu Takematsu, Yasunori Kozutsumi, Yukishige Ito, Yoshiki Yamaguchi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 674 KB

english, 2010

21

Thioester-assisted α-sialylation reaction

Shinya Hanashima, Shoji Akai, Ken-ichi Sato

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 197 KB

english, 2008

22

Synthesis of the starfish ganglioside AG2 pentasaccharide

Shinya Hanashima, Yoshiki Yamaguchi, Yukishige Ito, Ken-ichi Sato

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 260 KB

english, 2009

23

A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(α-d-sulfoquinovosyl)-glyceride with stearic acid

Chikako Murakami, Takayuki Yamazaki, Shinya Hanashima, Shunya Takahashi, Masaharu Takemura, Shonen Yoshida, Keisuke Ohta, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2003

Language:

english

File:

PDF, 305 KB

english, 2003

24

Structure-Activity Relationship of a Novel Group of Mammalian DNA Polymerase Inhibitors, Synthetic Sulfoquinovosylacylglycerols

Shinya Hanashima, Yoshiyuki Mizushina, Keisuke Ohta, Takayuki Yamazaki, Fumio Sugawara, Kengo Sakaguchi

Journal:

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

25

Anti-tumor Effect of Chemically Synthesized Sulfolipids Based on Sea Urchin's Natural Sulfonoquinovosylmonoacylglycerols

Hiroeki Sahara, Shinya Hanashima, Takayuki Yamazaki, Shunya Takahashi, Fumio Sugawara, Seiji Ohtani, Masako Ishikawa, Yoshiyuki Mizushina, Keisuke Ohta, Kumiko Shimozawa, Shinsei Gasa, Kouichi Jimbow,

Journal:

Year:

2002

Language:

english

File:

PDF, 2.14 MB

english, 2002

26

Total Synthesis of Sialylated Glycans Related to Avian and Human Influenza Virus Infection

Shinya Hanashima, Peter H. Seeberger

Journal:

Chemistry – An Asian Journal

Year:

2007

Language:

english

File:

PDF, 379 KB

english, 2007

27

Specific Interaction between an Oligosaccharide on the Tumor Cell Surface and the Novel Antitumor Agents, Sulfoquinovosylacylglycerols

Keisuke Ohta, Yoshiyuki Mizushina, Takayuki Yamazaki, Shinya Hanashima, Fumio Sugawara, Kengo Sakaguchi

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 285 KB

english, 2001

28

NMR characterization of intramolecular interaction of osteopontin, an intrinsically disordered protein with cryptic integrin-binding motifs

Yoshiki Yamaguchi, Shinya Hanashima, Hirokazu Yagi, Yutaka Takahashi, Hiroaki Sasakawa, Eiji Kurimoto, Takeshi Iguchi, Shigeyuki Kon, Toshimitsu Uede, Koichi Kato

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

29

Synthesis of β(1,3) oligoglucans exhibiting a Dectin-1 binding affinity and their biological evaluation

Hiroshi Tanaka, Tetsuya Kawai, Yoshiyuki Adachi, Shinya Hanashima, Yoshiki Yamaguchi, Naohito Ohno, Takashi Takahashi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

30

Characterization of Inhibitor-Bound α-Synuclein Dimer: Role of α-Synuclein N-Terminal Region in Dimerization and Inhibitor Binding

Yoshiki Yamaguchi, Masami Masuda, Hiroaki Sasakawa, Takashi Nonaka, Shinya Hanashima, Shin-ichi Hisanaga, Koichi Kato, Masato Hasegawa

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.64 MB

english, 2010

31

Structural Basis for Oligosaccharide Recognition of Misfolded Glycoproteins by OS-9 in ER-Associated Degradation

Tadashi Satoh, Yang Chen, Dan Hu, Shinya Hanashima, Kazuo Yamamoto, Yoshiki Yamaguchi

Journal:

Year:

2010

Language:

english

File:

PDF, 1.61 MB

english, 2010

32

Overproduction of anti-Tn antibody MLS128 single-chain Fv fragment in Escherichia coli cytoplasm using a novel pCold-PDI vector

Ganesh P. Subedi, Tadashi Satoh, Shinya Hanashima, Akemi Ikeda, Hiroshi Nakada, Reiko Sato, Mamoru Mizuno, Noriyuki Yuasa, Yoko Fujita-Yamaguchi, Yoshiki Yamaguchi

Journal:

Protein Expression and Purification

Year:

2012

Language:

english

File:

PDF, 737 KB

english, 2012

33

Structure–function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors

Chikako Murakami, Takayuki Yamazaki, Shinya Hanashima, Shunya Takahashi, Keisuke Ohta, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 201 KB

english, 2002

34

Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation

Keisuke Ohta, Shinya Hanashima, Yoshiyuki Mizushina, Takayuki Yamazaki, Mineo Saneyoshi, Fumio Sugawara, Kengo Sakaguchi

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2000

Language:

english

File:

PDF, 850 KB

english, 2000

35

Structural Relationship of Lithocholic Acid Derivatives Binding to the N-Terminal 8-kDa Domain of DNA Polymerase β †

Mizushina, Yoshiyuki, Kasai, Nobuyuki, Miura, Katsumi, Hanashima, Shinya, Takemura, Masaharu, Yoshida, Hiromi, Sugawara, Fumio, Sakaguchi, Kengo

Journal:

Year:

2004

Language:

english

File:

PDF, 365 KB

english, 2004

36

A solution 17O-NMR approach for observing an oxidized cysteine residue in Cu,Zn-superoxide dismutase

Hanashima, Shinya, Fujiwara, Noriko, Matsumoto, Kana, Iwasaki, Noriyuki, Zheng, Guo-qing, Torigoe, Hidetaka, Suzuki, Keiichiro, Taniguchi, Naoyuki, Yamaguchi, Yoshiki

Journal:

Chemical Communications

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

37

NMR study of short β(1-3)-glucans provides insights into the structure and interaction with Dectin-1

Hanashima, Shinya, Ikeda, Akemi, Tanaka, Hiroshi, Adachi, Yoshiyuki, Ohno, Naohito, Takahashi, Takashi, Yamaguchi, Yoshiki

Journal:

Glycoconjugate Journal

Year:

2014

Language:

english

File:

PDF, 733 KB

english, 2014

38

Difucosylation of chitooligosaccharides by eukaryote and prokaryote α1,6-fucosyltransferases

Ihara, Hideyuki, Hanashima, Shinya, Tsukamoto, Hiroki, Yamaguchi, Yoshiki, Taniguchi, Naoyuki, Ikeda, Yoshitaka

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2013

Language:

english

File:

PDF, 934 KB

english, 2013

39

NMR study into the mechanism of recognition of the degree of polymerization by oligo/polysialic acid antibodies

Hanashima, Shinya, Sato, Chihiro, Tanaka, Hiroshi, Takahashi, Takashi, Kitajima, Ken, Yamaguchi, Yoshiki

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

40

Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress

Tsutsui, Ayumi, Imamaki, Rie, Kitazume, Shinobu, Hanashima, Shinya, Yamaguchi, Yoshiki, Kaneda, Masato, Oishi, Shinya, Fujii, Nobutaka, Kurbangalieva, Almira, Taniguchi, Naoyuki, Tanaka, Katsunori

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 938 KB

english, 2014

41

Synthesis of N-glycan units for assessment of substrate structural requirements of N-acetylglucosaminyltransferase III

Hanashima, Shinya, Korekane, Hiroaki, Taniguchi, Naoyuki, Yamaguchi, Yoshiki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 598 KB

english, 2014

42

13C-NMR quantification of proton exchange at LewisX hydroxyl groups in water

Hanashima, Shinya, Kato, Koichi, Yamaguchi, Yoshiki

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 809 KB

english, 2011

43

Stabilization of β-peptide helices by direct attachment of trifluoromethyl groups to peptide backbones

Cho, Joonil, Sawaki, Kyohei, Hanashima, Shinya, Yamaguchi, Yoshiki, Shiro, Motoo, Saigo, Kazuhiko, Ishida, Yasuhiro

Journal:

Chemical Communications

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

44

JSPS Asian Core Program: 7 th & 8 th ICCEOCA (Phase II/NICCEOCA-3 & -4), 2 nd & 3 rd Junior ICCEOCA, and Partly IUPAC Asian Project

Isobe, Minoru, Murata, Michio, Hanashima, Shinya, Nishida, Atsushi, Loh, Teck Peng, Rahman, Noorsaadah Abd., Thasana, Nopporn, Chittchang, Montakarn

Journal:

Chemistry – An Asian Journal

Year:

2014

Language:

english

File:

PDF, 2.45 MB

english, 2014

45

Axial Hydrogen at C7 Position and Bumpy Tetracyclic Core Markedly Reduce Sterol’s Affinity to Amphotericin B in Membrane

Nakagawa, Yasuo, Umegawa, Yuichi, Nonomura, Kenichi, Matsushita, Naohiro, Takano, Tetsuro, Tsuchikawa, Hiroshi, Hanashima, Shinya, Oishi, Tohru, Matsumori, Nobuaki, Murata, Michio

Journal:

Year:

2015

Language:

english

File:

PDF, 2.05 MB

english, 2015

46

Microfluidic Mixing of Polyamine with Acrolein Enables the Detection of the [4+4] Polymerization of Intermediary Unsaturated Imines: The Properties of a Cytotoxic 1,5-Diazacyclooctane Hydrogel

Pradipta, Ambara, Tsutsui, Ayumi, Ogura, Akihiro, Hanashima, Shinya, Yamaguchi, Yoshiki, Kurbangalieva, Almira, Tanaka, Katsunori

Journal:

Year:

2014

Language:

english

File:

PDF, 414 KB

english, 2014

47

Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane

Yamamoto, Tomoya, Umegawa, Yuichi, Tsuchikawa, Hiroshi, Matsumori, Nobuaki, Hanashima, Shinya, Murata, Michio, Haser, Resul, Rawlings, Bernard J., Caffrey, Patrick

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

48

Polymer - Resin HybridCapture - Release Strategy for Rapid OligosaccharideConstruction

Hanashima, Shinya, Manabe, Shino, Ito, Yukishige

Journal:

Year:

2003

Language:

english

File:

PDF, 83 KB

english, 2003

49

An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin

Matsumoto, Yoshitaka, Sahara, Hiroeki, Fujita, Tatsuya, Shimozawa, Kumiko, Takenouchi, Mika, Torigoe, Toshihiko, Hanashima, Shinya, Yamazaki, Takeyuki, Takahashi, Shunya, Sugawara, Fumio, Mizushina, Y

Journal:

Transplantation Journal

Year:

2002

Language:

english

File:

PDF, 332 KB

english, 2002

50

Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N -glycan

Nagae, Masamichi, Ikeda, Akemi, Hanashima, Shinya, Kojima, Takumi, Matsumoto, Naoki, Yamamoto, Kazuo, Yamaguchi, Yoshiki

Journal:

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016